In my lifetime I have lived an amazing number of places. Some of those places have been exceptionally nice. Others have been… well… Hicksville. In Jesus’ day, people who lived in Samaria were considered hicks by people who lived in Jerusalem.
Technically Jesus was born in Bethlehem just south of Jerusalem, so he was every bit as “pure” as the Pharisees who derided him. Of course, he was raised in Galilee north of Samaria in a town called Nazareth. Not the most prestigious place on the planet, but not in Samaria, either. To suggest that Jesus was a Samaritan was an insult coming from a Jew, and to say that someone was demon-possessed was far worse than just an insult.
The Jews answered him, “Aren’t we right in saying that you are a Samaritan and demon-possessed?”
“I am not possessed by a demon,” said Jesus, “but I honor my Father and you dishonor me.”